CONSERVED CHROMATIN REGULATORS CONTROL THE TRANSCRIPTIONAL IMMUNE RESPONSE TO INTRACELLULAR PATHOGENS IN CAENORHABDITIS ELEGANS.

Conserved chromatin regulators control the transcriptional immune response to intracellular pathogens in Caenorhabditis elegans.

Robust transcriptional responses are critical for defense against infection.However, unrestrained immune responses can cause negative impacts such as damaging inflammation and Air Purifier slowed development.Here, we find that a class of transcriptional regulators previously associated with regulation of development in Caenorhabditis elegans, is al

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Tumor-Induced Osteomalacia in a Patient With FGF23-Amplified Lung Adenocarcinoma and FGF23-Deleted SCLC: Case Report

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by ectopic fibroblast growth factor-23 (FGF23) production.We Video Accessories report a unique case of a 78-year-old female patient with refractory hypophosphatemia, ultimately diagnosed as TIO, in the context of two metastatic primary lung cancers: adenocarcinoma and

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Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: A structure-based drug designing approach

Background & objectives: Cysteine proteases (falcipains), a papain-family of enzymes of Plasmodium falciparum, are responsible for haemoglobin degradation and thus necessary for its survival during asexual life cycle phase inside the human red blood cells while remaining non-functional for the human body.Therefore, these can act as potential target

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Network Topology Inference Based on Subset Structure Fusion

Network topology Lip Gloss measurement is an important component in network research.Network tomography is able to accurately infer network topology by using end-to-end measurement without cooperation of internal routers.Unfortunately, traditional network tomography methods can not accurately estimate topology in the non-stationary network due to t

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